Discover CBGa, cannabigerolic acid
You've probably already heard of CBG, cannabigerol. But have you heard of CBGa, cannabigerolic acid? This is the cannabinoid precursor to CBG, found in the hemp and cannabis plants. In the rest of this article, we'll tell you absolutely everything you need to know about this molecule, which is much less well known than CBG, CBD or even THC, but whose role, ultimately, is essential.
What is CBGa?
How was CBGa discovered?
Does CBGa really play a role?
Possible applications for CBGa
Are CBGa-based products available?
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What is CBGa?
CBGa, for cannabigerolic acid, is a so-called minor cannabinoid. It is produced in the cannabis plant. Its role is essential. In fact, this cannabinoid is produced in the plant's trichomes and performs a so-called protective function.
How does it work? CBGa is responsible for the production of virtually all other cannabinoids. Imagine the cannabis plant as a pyramid, with CBD, THC and CBG at the bottom.
The first position would be occupied by CBGa. This molecule presupposes the appearance of THCa (tetrahydrocannabinolic acid), CBDa (cannabidiolic acid) or CBCA (cannabichromenic acid) via a whole chemical process. Then, depending on the variety of hemp and cannabis, CBGa is converted into CBG, THC or CBD after decarboxylation.
How was CBGa discovered?
CBG was one of the first cannabinoids to be discovered. Over 50 years ago, Israeli researchers were able to isolate it. Some thirty years later, Japanese researchers announced the existence of CBGa, claiming that this molecule was a precursor to CBG.
However, very little is known about this cannabinoid , as the number of studies on the subject is quite limited. Indeed, scientists prefer to focus on THC/THCa and CBD/CBDa, whose effects are likely to be more beneficial to the body.
Does the CBGa really play a role?
For that matter, does CBGa, cannabigerolic acid, really have an impact on the body? Until recently, most research on CBGa has focused on its conversion into THCa.
However, some preclinical studies have focused on the possible effects of this molecule. A series of simulations could prove that CBGa :
- Inhibits oxidative stress;
- Optimizes the destruction of colon cancer cells;
- Would be an interesting analgesic, as well as antibacterial;
- Stimulates appetite.
However, further research is still required. As explained above, at this stage, studies on CBGa are still in their infancy.
Possible applications for CBGa
Research on this cannabinoid is scarce, but early studies show some potential applications, including on:
- Cardiovascular diseases;
- Metabolic disorders.
Cardiovascular diseases
CBGa is a cannabinoid that could enable patients suffering from type 1 and type 2 diabetes to fight more effectively against the complications of certain diseases linked to cardiovascular disorders.
A recent study showed that CBGa inhibits an enzyme that contributes significantly to the oxidative stress that leads to heart problems.
The researchers concluded that this compound is a promising agent for the prevention and treatment of diabetic complications.
Metabolic disorders
CBGa could also help patients with metabolic disorders. In 2019, a computer simulation study examined the molecule's role in activating specific receptors that help metabolism to regulate itself.
When these receptors don't function properly, individuals develop diabetes or other diseases. The study found that CBGa activated the receptors and stimulated lipid metabolism, which could be useful in treating type 2 diabetes.
CBGa is a molecule with a wide range of effects on the human body. For the moment, there are too few studies to really demonstrate its effects on the endocannabinoid system. However, with the democratization of hemp, it's a safe bet that more and more research will be carried out, both now and in the years to come.
Are CBGa-based products available?
There aren't really any CBD products enriched with CBGa. However, there are two options for consumers who want to learn more and enjoy the potential benefits of this cannabinoid.
The first solution is to turn to oils CBD or Flowers and hash CBD enriched with CBG. CBGa is the precursor molecule of CBG. In fact, you'll be able to get a taste of what it feels like.
You can also turn to oils CBD full spectrum. These products contain all the cannabinoids, from CBGa to THC (in small quantities), for the surrounding effect.
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oils, Flowers or hash CBD enriched with CBG, for a simply exceptional experience. Do you run your own CBD shop or e-shop? Don't hesitate to contact us for further information.
